Newcastle Disease Virus Induces Profound Lymphoid Depletion with Different Patterns of Necroptosis, Necrosis, and Oxidative DNA Damage in Bursa, Spleen, and Other Lymphoid Tissues

This study delves into the pathogenesis of virulent genotype VII strains of the Newcastle disease virus (NDV), focusing on experimentally infected birds. Predominant and consistent lesions observed include bursal atrophy and extensive depletion of all lymphoid tissues. Immunohistochemistry (IHC) ana...

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Principais autores:	Mohammad Rabiei, Milton M. McAllister, Natalie R. Gassman, Kevin J. Lee, Sydney Acton, Dieter Liebhart, Wai Yee Low, Farhid Hemmatzadeh
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-07-01
Colecção:	Pathogens
Assuntos:	Newcastle disease virus (NDV) lymphoid depletion necroptosis apoptosis repair assisted damage detection (RADD) oxidative damage
Acesso em linha:	https://www.mdpi.com/2076-0817/13/8/619
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