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cTfh Cell Activation and Changes in BTLA and LAG-3 Expression Differentially Associate With Poor Pregnancy Outcome in Plasmodium falciparum Placental Malaria

Continuous exposure to antigens drives the activation of circulating T follicular helper (cTfh) cells, promoting high-affinity antibody production. However, sustained stimulation may impair their function through the upregulation of immunoregulatory markers like B and T lymphocyte attenuator (BTLA)...

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Bibliografische Detailangaben
Hauptverfasser: Bernard Marie Zambo Bitye, Chris Marco Mbianda Nana, Bodin Darcisse Kwanou Tchakounte, Balotin Fogang, Berenice Kenfack Tekougang Zangue, Reine Seumko’o Medouen Ndeumou, Lawrence Ayong, Rosette Megnekou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2026-01-01
Schriftenreihe:Journal of Immunology Research
Online-Zugang:http://dx.doi.org/10.1155/jimr/6467951
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