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Data-driven asthma endotypes defined from blood biomarker and gene expression data.

The diagnosis and treatment of childhood asthma is complicated by its mechanistically distinct subtypes (endotypes) driven by genetic susceptibility and modulating environmental factors. Clinical biomarkers and blood gene expression were collected from a stratified, cross-sectional study of asthmati...

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Principais autores: Barbara Jane George, David M Reif, Jane E Gallagher, ClarLynda R Williams-DeVane, Brooke L Heidenfelder, Edward E Hudgens, Wendell Jones, Lucas Neas, Elaine A Cohen Hubal, Stephen W Edwards
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC4314082?pdf=render
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