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Novel and recurrent genetic variants of VHL, SDHB, and RET genes in Chinese pheochromocytoma and paraganglioma patients

Background: Pheochromocytoma and paraganglioma (PPGL) are rare neuroendocrine tumors arising from chromaffin cells in the adrenal medulla and extra-adrenal ganglia, respectively. The study was aimed to investigate the clinical and genetic characteristics of 22 individuals from six families.Methods:...

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Principais autores: Chong Li, Jingyi Li, Chao Han, Ting Wang, Lixia Zhang, Zhifang Wang, Tingting Wang, Lijun Xu, Guangzhao Qi, Guijun Qin, Xialian Li, Lili Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-03-01
coleção:Frontiers in Genetics
Assuntos:
pheochromocytoma
paraganglioma
VHL
SDHB
RET
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fgene.2023.959989/full
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