Effect of Hydroxytyrosol Derivatives of Donepezil on the Activity of Enzymes Involved in Neurodegenerative Diseases and Oxidative Damage

Monoamine oxidase and xanthine oxidase inhibitors represent useful multi-target drugs for the prevention, attenuation, and treatment of oxidative damage and neurodegenerative disorders. Chimeric molecules, constituted by naturally derived compounds linked to drugs, represent lead compounds to be exp...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Antonio D’Errico, Rosarita Nasso, Rosario Rullo, Jessica Maiuolo, Paola Costanzo, Sonia Bonacci, Manuela Oliverio, Emmanuele De Vendittis, Mariorosario Masullo, Rosaria Arcone
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2024-01-01
Schriftenreihe:	Molecules
Schlagworte:	hydroxytyrosol-donepezil hybrid inflammatory diseases neurodegenerative disorders monoamine oxidase (MAO) xanthine oxidase (XO) multitargeting agents
Online-Zugang:	https://www.mdpi.com/1420-3049/29/2/548
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