Novel anti-inflammatory and analgesic agents: synthesis, molecular docking and in vivo studies

Twelve new derivatives of benzothiazole bearing benzenesulphonamide and carboxamide were synthesised and investigated for their in vivo anti-inflammatory, analgesic and ulcerogenic activities. Molecular docking showed an excellent binding interaction of the synthesised compounds with the receptors,...

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Hlavní autoři:	David Izuchukwu Ugwu, Uchechukwu Christopher Okoro, Pius Onyeoziri Ukoha, Astha Gupta, Sunday N. Okafor
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis Group 2018-01-01
Edice:	Journal of Enzyme Inhibition and Medicinal Chemistry
Témata:	Analgesic anti-inflammatory benzothiazole carboxamide oral bioavailability sulphonamide ulcerogenic index
On-line přístup:	http://dx.doi.org/10.1080/14756366.2018.1426573
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