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Real-world evidence for repurposing hydralazine as a potential epigenetic modulator for psoriasis: a 16-year retrospective nationwide cohort study

Abstract Background Dysregulated DNA methylation and hypertension (HTN) are closely associated with the development of psoriasis. However, the impact of the vasodilator hydralazine (HLZ), which also inhibits DNA methyltransferase, on psoriasis risk remains unclear. This study investigated the associ...

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Bibliografski detalji
Glavni autori: Shou-En Wu, Wei‑Ming Wang, Chih-Tsung Hung, Chi-Hsiang Chung, Wu-Chien Chien, Bing-Heng Yang
Format: Artigo
Jezik:Inglês
Izdano: BMC 2025-11-01
Serija:Journal of Translational Medicine
Teme:
Online pristup:https://doi.org/10.1186/s12967-025-07322-4
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