Targeting the Interaction of GABAB Receptors With CHOP After an Ischemic Insult Restores Receptor Expression and Inhibits Progressive Neuronal Death

GABAB receptors control neuronal excitability via slow and prolonged inhibition in the central nervous system. One important function of GABAB receptors under physiological condition is to prevent neurons from shifting into an overexcitation state which can lead to excitotoxic death. However, under...

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Autors principals:	Musadiq A. Bhat, Abolghasem Esmaeili, Elena Neumann, Karthik Balakrishnan, Dietmar Benke
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-03-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	GABAB receptor neuroprotection interfering peptide CHOP cerebral ischemia oxygen and glucose deprivation (OGD)
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2022.870861/full
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