EX527, a sirtuins 1 inhibitor, sensitizes T-cell leukemia to death receptor-mediated apoptosis by downregulating cellular FLICE inhibitory protein
Death receptor-mediated extrinsic apoptosis system had been developed as a promising therapeutic strategy in clinical oncology, such as TRAIL therapy. However, multiple studies have demonstrated that TRAIL resistance is the biggest problem for disappointing clinical trials despite preclinical succes...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis Group
2024-12-01
|
| Collection: | Cancer Biology & Therapy |
| Sujets: | |
| Accès en ligne: | https://www.tandfonline.com/doi/10.1080/15384047.2024.2402588 |
| Tags: |
Pas de tags, Soyez le premier à ajouter un tag!
|