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Phylogenomic Diversity Elucidates Mechanistic Insights into Lyme Borreliae-Host Association

ABSTRACT Host association—the selective adaptation of pathogens to specific host species—evolves through constant interactions between host and pathogens, leaving a lot yet to be discovered on immunological mechanisms and genomic determinants. The causative agents of Lyme disease (LD) are spirochete...

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Autori principali: Matthew Combs, Ashley L. Marcinkiewicz, Alan P. Dupuis, April D. Davis, Patricia Lederman, Tristan A. Nowak, Jessica L. Stout, Klemen Strle, Volker Fingerle, Gabriele Margos, Alexander T. Ciota, Maria A. Diuk-Wasser, Sergios-Orestis Kolokotronis, Yi-Pin Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2022-08-01
Serie:mSystems
Soggetti:
host association
Borrelia
complement
phylogenomics
plasmid diversity
Accesso online:https://journals.asm.org/doi/10.1128/msystems.00488-22
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