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Germline HLA-I genotypes predict pathologic response and survival outcomes in esophageal cancer patients undergoing neoadjuvant immunochemotherapy: a retrospective cohort study

Abstract Background Neoadjuvant immunochemotherapy (nICT) has reshaped the treatment paradigm for locally advanced esophageal cancer (EC), but patient responses remain highly heterogeneous. Reliable biomarkers to predict therapeutic benefit are urgently needed. Class I human leukocyte antigen (HLA-I...

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Autors principals: Willis Wasonga Omindo, Qi Wang, Siyou Deng, Ruijie Zhang, Wei Sun, Li Zhang, Ni Zhang
Format: Artigo
Idioma:Inglês
Publicat: BMC 2026-05-01
Col·lecció:World Journal of Surgical Oncology
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Accés en línia:https://doi.org/10.1186/s12957-026-04374-8
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