Vandetanib in a Child Affected by Neurofibromatosis Type 1 and Medullary Thyroid Carcinoma with Both NF1 and Homozygous RET Proto-oncogen Germ-line Mutations

Cases of neurofibromatosis type 1 (NF1)-associated medullary thyroid carcinoma (MTC) or C-cell hyperplasia are rarely associated with other endocrine tumors or cases with a multiple endocrine neoplasia type 2. In these patients, mutations were detected in the NF1 gene but no mutations were detected...

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Autors principals:	Begümhan Demir Gündoğan, Fatih Sağcan, Sevcan Tuğ Bozdoğan, Yüksel Balcı, Ferah Tuncel Daloğlu, Elvan Cağlar Çıtak
Format:	Artigo
Idioma:	Inglês
Publicat:	Pediatric Endocrinology and Diabetes Society 2021-09-01
Col·lecció:	JCRPE
Matèries:	medullary thyroid carcinoma vandetanib ret proto-oncogene nf1 gene children
Accés en línia:	http://www.jcrpe.org/archives/archive-detail/article-preview/vandetanib-in-a-child-affected-by-neurofibromatosi/39876
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