Proteasome-mediated degradation of long-range nucleases negatively regulates resection of DNA double-strand breaks

Summary: Homologous recombination is initiated by the nucleolytic degradation (resection) of DNA double-strand breaks (DSBs). DSB resection is a two-step process. In the short-range step, the MRX (Mre11-Rad50-Xrs2) complex, together with Sae2, incises the 5′-terminated strand at the DSB end and rese...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Marco Gnugnoli, Carlo Rinaldi, Erika Casari, Paolo Pizzul, Diego Bonetti, Maria Pia Longhese
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2024-07-01
Cyfres:	iScience
Pynciau:	Model organism Molecular genetics Properties of biomolecules Techniques in genetics
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2589004224015980
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!