Fixed-parameter tractable sampling for RNA design with multiple target structures

Abstract Background The design of multi-stable RNA molecules has important applications in biology, medicine, and biotechnology. Synthetic design approaches profit strongly from effective in-silico methods, which substantially reduce the need for costly wet-lab experiments. Results We devise a novel...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Stefan Hammer, Wei Wang, Sebastian Will, Yann Ponty
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2019-04-01
Edice:	BMC Bioinformatics
Témata:	RNA multi-target design RNA secondary structure Multi-dimensional Boltzmann sampling # P-hardness of RNA design
On-line přístup:	http://link.springer.com/article/10.1186/s12859-019-2784-7
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!