Expression of selected pathway-marker genes in human urothelial cells exposed chronically to a non-cytotoxic concentration of monomethylarsonous acid

Bladder cancer has been associated with chronic arsenic exposure. Monomethylarsonous acid [MMA(III)] is a metabolite of inorganic arsenic and has been shown to transform an immortalized urothelial cell line (UROtsa) at concentrations 20-fold less than arsenite. MMA(III) was used as a model arsenical...

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Principais autores:	Matthew Medeiros, Tam Minh Le, Daniel Troup, Petr Novak, A. Jay Gandolfi
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2014-01-01
叢編:	Toxicology Reports
主題:	Arsenic Arsenical Urinary bladder Carcinogenesis Gene expression Urothelial cells PCR array
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2214750014000481
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