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Assessment of “Sameness” and/or Differences between Marketed Creams Containing Miconazole Nitrate Using a Discriminatory in vitro<i> </i>Release Testing (IVRT) Method

In vitro release testing (IVRT) provides an efficient method for the evaluation of drug release from semi-solid formulations. The aim of this research was to develop and validate a discriminatory IVRT system using vertical diffusion cells (VDCs) to assess generic topical products containing miconazo...

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Principais autores: Potiwa Purazi, Seeprarani Rath, Ashmita Ramanah, and Isadore Kanfer
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-02-01
coleção:Scientia Pharmaceutica
Assuntos:
ivrt
vertical diffusion cells (vdcs)
miconazole nitrate
topical dermatological creams
fda supac-ss guidance
acceptance criteria
method validation
discriminatory ability
q1/q2/q3 properties.
Acesso em linha:https://www.mdpi.com/2218-0532/88/1/6
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