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CCB-4 and its sugar complexes induce mitotic catastrophe and p53-independent apoptosis through caspase-2 elevation and suppression of c-Myc in T47D cells

Adding boron to curcumin analogs enhances their ability to inhibit cell growth and facilitates their detection within cells. Derivatives of diboronocurcumin are, therefore, promising options for cancer treatment. Our previous in silico analysis revealed that CCB-4 binds more tightly to proteins asso...

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Principais autores: Ni Putu Linda Laksmiani, Rohmad Yudi Utomo, Riris Istighfari Jenie, Yusuke Suenaga, Mitsunori Kirihata, Edy Meiyanto, Ratna Asmah Susidarti
Formato: Artigo
Idioma:Inglês
Publicado: Wolters Kluwer Medknow Publications 2026-04-01
Series:Journal of Advanced Pharmaceutical Technology & Research
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Acceso en liña:https://journals.lww.com/10.4103/JAPTR.JAPTR_311_25
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