Association between metformin use and disease progression in obese people with knee osteoarthritis: data from the Osteoarthritis Initiative—a prospective cohort study

Abstract Objective To examine whether metformin use was associated with knee cartilage volume loss over 4 years and risk of total knee replacement over 6 years in obese individuals with knee osteoarthritis. Methods This study analysed the Osteoarthritis Initiative participants with radiographic knee...

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Главные авторы:	Yuanyuan Wang, Sultana Monira Hussain, Anita E. Wluka, Yuan Z. Lim, François Abram, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Flavia M. Cicuttini
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2019-05-01
Серии:	Arthritis Research & Therapy
Предметы:	Metformin Osteoarthritis Cartilage Total knee replacement
Online-ссылка:	http://link.springer.com/article/10.1186/s13075-019-1915-x
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