Evaluation of tissue-engineered blood vessels as three-dimensional in vitro testing system in cardiovascular research

BackgroundDisturbed crosstalk between endothelial cells (ECs) and vascular smooth muscle cells (SMCs) has an important role in intimal hyperplasia and restenosis after vascular interventions, however, the exact pathomechanisms are incompletely understood. Current preclinical models inadequately reca...

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Principais autores:	Diana M. Rojas-González, Frederic Wolf, Nicole Schaaps, Roberta A. Florescu, Carolina Bienzeisler, Rahma Shahin, Celine Brinkmann, Pakhwan Nilcham, Felix Vogt, Stefan Jockenhoevel, Anne Turoni-Glitz, Petra Mela
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2026-05-01
Series:	Frontiers in Bioengineering and Biotechnology
Assuntos:	cellular crosstalk in vitro testing intimal hyperplasia stent implantation tissue engineering
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fbioe.2026.1729469/full
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