Loeys-Dietz syndrome subtypes exhibit distinct clinical behavior and aortic cellular transcriptomic profilesCentral MessagePerspective

Objectives: Loeys-Dietz syndrome comprises genetically discrete subtypes of varying clinical severity. This study integrates longitudinal Loeys-Dietz syndrome clinical outcomes after aortic root replacement with transcriptomic analysis of aortic smooth muscle cell dysregulation to investigate mechan...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Albert J. Pedroza, MD, Alex R. Dalal, MD, Jennifer Kim, MD, Matthew Duda, MD, Emily Tognozzi, PA-C, Casey Gilles, BS, D. Craig Miller, MD, Michael P. Fischbein, MD, PhD
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2025-08-01
Σειρά:	JTCVS Open
Θέματα:	aortic aneurysm aortic arch aortic root replacement Loeys-Dietz syndrome RNA sequencing smooth muscle cell
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2666273625002190
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