Connecting the dots: microstructural properties of white matter hyperintensities predict longitudinal cognitive changes in ageing

This study investigates the relationship between white matter hyperintensities (WMHs) and longitudinal cognitive decline in older adults. Using data from The Irish Longitudinal Study on Ageing (TILDA), we examined WMH characteristics, including volume, location, and microstructural integrity, in a c...

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Autori principali:	Michael Courtney, Daniel Carey, Stephen Murphy, Silvin Knight, James F. Meaney, Rose Anne Kenny, Céline De Looze
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2025-02-01
Serie:	Frontiers in Aging Neuroscience
Soggetti:	white matter hyperintensities cognitive decline aging vascular dementia cardiovascular risk factors neuroimaging
Accesso online:	https://www.frontiersin.org/articles/10.3389/fnagi.2025.1520069/full
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