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Exploring genetic associations between immune cells and hypertensive disorder of pregnancy using Mendelian randomization

Abstract Background Observational epidemiological studies suggested that immunological dysregulation and inflammation play a significant role in the placental and renal dysfunction that leads to maternal hypertension. The immunophenotypes' possible causalities with hypertensive disease of pregnancy...

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Principais autores: Jingting Liu, Yijun Dong, Yawei Zhou, Wendi Wang, Yan Li, Jianying Pei
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-11-01
Serier:BMC Pregnancy and Childbirth
Fag:
Hypertensive disorders of pregnancy (HDP)
Immunophenotype
Mendelian randomization
Causality
Mediation analysis
Online adgang:https://doi.org/10.1186/s12884-024-06950-w
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