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Two-Stage Priming of Allogeneic Natural Killer Cells for the Treatment of Patients with Acute Myeloid Leukemia: A Phase I Trial.

<h4>Unlabelled</h4>Human Natural Killer (NK) cells require at least two signals to trigger tumor cell lysis. Absence of ligands providing either signal 1 or 2 provides NK resistance. We manufactured a lysate of a tumour cell line which provides signal 1 to resting NK cells without signal 2. The tumo...

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Bibliografiske detaljer
Principais autores: Panagiotis D Kottaridis, Janet North, Maria Tsirogianni, Chloe Marden, Edward R Samuel, Sam Jide-Banwo, Sarah Grace, Mark W Lowdell
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2015-01-01
Serier:PLoS ONE
Online adgang:https://doi.org/10.1371/journal.pone.0123416
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