Establishment of a Pre-vascularized 3D Lung Cancer Model in Fibrin Gel—Influence of Hypoxia and Cancer-Specific Therapeutics

Lung cancer is the most frequently diagnosed cancer worldwide and the one that causes the highest mortality. In order to understand the disease and to develop new treatments, in vitro human lung cancer model systems which imitate the physiological conditions is of high significance. In this study, a...

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Principais autores:	Caroline Kniebs, Anja Elisabeth Luengen, Daniel Guenther, Christian Gabriel Cornelissen, Thomas Schmitz-Rode, Stefan Jockenhoevel, Anja Lena Thiebes
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-10-01
coleção:	Frontiers in Bioengineering and Biotechnology
Assuntos:	3D in vitro cancer models drug testing fibrin gels tumor model lung cancer
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fbioe.2021.761846/full
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