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Deubiquitinating Enzymes Related to Autophagy: New Therapeutic Opportunities?

Autophagy is an evolutionary conserved catabolic process that allows for the degradation of intracellular components by lysosomes. This process can be triggered by nutrient deprivation, microbial infections or other challenges to promote cell survival under these stressed conditions. However, basal...

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Principais autores: Anne-Claire Jacomin, Emmanuel Taillebourg, Marie-Odile Fauvarque
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2018-08-01
Serier:Cells
Fag:
autophagy
DUB
deubiquitinating enzymes
inhibitor
aggrephagy
mitophagy
chaperone-mediated autophagy
small-molecule
ubiquitin
ubiquitin proteases
Online adgang:http://www.mdpi.com/2073-4409/7/8/112
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