Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus

While it is clear that acute hippocampal injury or status epilepticus increases the production of new neurons in the adult dentate gyrus (DG), the effects of chronic epilepsy on dentate neurogenesis are unknown. We hypothesize that epileptogenic changes and spontaneous recurrent motor seizures (SRMS...

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Detalles Bibliográficos

Principais autores:	Bharathi Hattiangady, Muddanna S. Rao, Ashok K. Shetty
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2004-12-01
Series:	Neurobiology of Disease
Assuntos:	Adult neurogenesis Doublecortin Fibroblast growth factor-2 Insulin-like growth factor-1 Hippocampal inflammation Neural progenitors
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S0969996104001895
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