Molecular Mechanisms and Therapies of Colorectal Cancer

Colorectal cancer (CRC) is currently the third leading cause of cancer-related mortality, with 1.9 million incidence cases and 0.9 million deaths worldwide. The global number of new CRC cases is predicted to reach 3.2 million in 2040, based on the projection of aging, population growth, and human de...

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Detalhes bibliográficos
Autores corporativos: Cave, Donatella Delle, Ottaiano, Alessandro
Formato: Livro
Idioma:Inglês
Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2023
Assuntos:
bic Book Industry Communication::M Medicine
bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
colorectal cancer
miRNA
ceRNA
lncRNA
circRNA
sponging
noninvasive biomarkers
MiR-199b
tumor suppressor
prognosis
LARC
HOX
HOXB9
colorectal liver metastases
metastatic colorectal cancer
structural variants
common fragile sites
platinum therapy
stalled replication fork
surgical oncology
liver regeneration
immunology
hepatic tissue-resident memory T cells
liver neoplasms
neoplasm metastasis
proteomics
biomarkers
mass spectrometry
microRNA
hypoxia
hypoxia-regulated microRNAs
fatty acid synthase
lipid metabolism
colorectal cancer initiation
Apc mutation
epigenetics
methylation
biomarker
S-Adenosylmethionine
breast cancer
Notch
metastasis
EMT
targeted sequencing
inflammatory bowel diseases
colitis-associated cancer
phosphatidylinositol 3-kinase
sortilin
neurotensin
neurotensin receptor-3
soluble sortilin
cell signaling
cell morphology
colorectal carcinoma
early onset CRC
multi-omics
lymphovascular invasion
perineural invasion
DNA damage repair
DNA replication repair
MMR
base excision repair
FASN
CTLA4
HAVCR2
TGF-β signaling
targeting therapy
immune-suppressive
barrier properties
colon
heterogeneity
cytokines
tumor necrosis factor alpha
interleukin 10
tight junction proteins
1,2-dimethylhydrazine
rat
epithelial-to-mesenchymal transition
tumor-associated macrophages
Acesso em linha:https://directory.doabooks.org/handle/20.500.12854/96735
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