Polyamine Metabolism in Disease and Polyamine-Targeted Therapies

Polyamines are ubiquitous polycations essential for all cellular life. The most common polyamines in eukaryotes, spermine, spermidine, and putrescine, exist in millimolar intracellular concentrations that are tightly regulated through biosynthesis, catabolism, and transport. Polyamines interact with...

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Detalhes bibliográficos
Autor principal: Murray-Stewart, Tracy
Formato: Livro
Idioma:Inglês
Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2019
Assuntos:
QH301-705.5
Q1-390
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
protein synthesis in cancer
neuroblastoma
epigenetics
Drosophila imaginal discs
pneumococcal pneumonia
transgenic mice
spermidine/spermine N1-acetyl transferase
?-difluoromethylornithine
MYC
skeletal muscle
protein expression
curcumin
colorectal cancer
autophagy
human embryonic kidney 293 (HEK293)
melanoma
tumor immunity
Snyder-Robinson Syndrome
Streptococcus pneumoniae
B-lymphocytes
autoimmunity
spermine oxidase
cell differentiation
diferuloylmethane
immunity
antizyme
transgenic mouse
polyamine
hirsutism
chemoprevention
CRISPR
transglutaminase
polyamine analogs
NF-?B
spermine synthase
atrophy
aging
oxidative stress
mast cells
African sleeping sickness
pancreatic ductal adenocarcinoma
eflornithine
carcinogenesis
ornithine decarboxylase
polyamine transport inhibitor
putrescine
neutrophils
spermidine
untranslated region
spermine
polyphenol
M2 macrophages
polyamine transport system
metabolism
difluoromethylorthinine
DFMO
antizyme inhibitors
capsule
polyamine transport
eosinophils
MCF-7 cells
difluoromethylornithine
polyamine metabolism
mutant BRAF
polyamines
cadaverine
proteomics
airway smooth muscle cells
breast cancer
X-linked intellectual disability
complementation
T-lymphocytes
bis(ethyl)polyamine analogs
antizyme 1
cancer
osteosarcoma
Acesso em linha:https://directory.doabooks.org/handle/20.500.12854/56626
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