Steroid Compounds with Potential Biological Activity

Steroids are a large group of compounds whose structure is based on a 17-carbon skeleton, with a specific cyclopentanoperhydrophenanthrene ring system. Natural steroids have been fine-tuned through evolution to build membranes; act as chemical messengers that regulate metabolic, immune and reproduct...

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Detalhes bibliográficos
Corporate Authors: Savić, Marina, Mernyák, Erzsébet, Ajdukovic, Jovana, Jovanović-Šanta, Suzana
Formato: Livro
Idioma:Inglês
Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2023
Assuntos:
bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
4-azasteroids
4-azapregnenes
aldol condensation
molecular docking
antiproliferative activity
Paracaudina chilensis
Molpadida
triterpene glycosides
chilensosides
sea cucumber
cytotoxic activity
26-thiodiosgenin
thiol oxidation
sulfoxides
sulfones
sapogenins
steroids
antimicrobial activity
cytotoxicity
breast cancer
endocrine therapy
endocrine resistance
aromatase inhibitors
exemestane
oxymestane
anti-cancer properties
multi-target compounds
aromatase
estrogen receptor
androgen receptor
Chan–Lam reaction
diaryl ether
13α-estrone
antiproliferative effect
tubulin polymerization
molecular dynamics
oximes
chemistry
antitumor
anti-inflammatory
antibacterial
antifungal
antiviral
triterpenoids
isoprenoid lipids
anti-neoplastic
anti-fungal
anti-bacterial
anti-viral
fungal endophytes
plants
marine invertebrates
furanosteroids
fungi
marine organisms
diacetoxy-5α-cholestane
crystal structure HSA binding
multi-spectroscopy
DFT
steroid dimers
1,4-phenylene-linked dimers
montmorillonite
DHEA
cholesterol
cation channels
TRPML1
bioisostere
estrogens
ring cleavage
protective groups
pyridines
pyrimidines
cyclization
antimetabolites
cell growth inhibition
gene expression
HeLa cells
in vitro culture
Acesso em linha:https://directory.doabooks.org/handle/20.500.12854/132467
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