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Physics of Protein Folding, Misfolding, and Intrinsic Disorder: A Themed Issue in Honour of Professor Vladimir Uversky on the Occasion of His 60th Birthday

This Special Issue of Biomolecules, “Physics of Protein Folding, Misfolding, and Intrinsic Disorder: A Themed Issue in Honour of Professor Vladimir Uversky on the Occasion of His 60th Birthday”, is a dedication to one of the discoverers of IDPs. This collection is a small token of the respect, admir...

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Detalhes bibliográficos
Corporate Authors:	Kulkarni, Prakash, Brocca, Stefania, Dunker, Keith, Longhi, Sonia
Formato:	Livro
Idioma:	Inglês
Publicado em:	MDPI - Multidisciplinary Digital Publishing Institute 2023
Assuntos:	thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences charge clustering polyelectrolytes average shape of conformational ensembles charged-residue patterning hydrodynamic radius solvent-accessible surface area proline content conformational compactness ellipsoid model intrinsically disordered proteins (IDPs) intrinsically disordered protein regions (IDRs) LC–MS/MS IUPred analysis Ostrinia nubilalis cold hardiness intrinsic disorder intrinsically disordered proteins intrinsic disordered regions disorder scale disorder propensity amino acids amino acid bias predictive performance disorder prediction SARS-CoV-2 COVID-19 IDP RNA NMR pH liquid-liquid phase separation protein solubility protein disorder mutations bioinformatics kinetics fluorescence site-directed mutagenesis protein–protein interactions SH2 domains Crkl Paxillin Calvin-Benson-Bassham cycle conditionally disordered protein history of modern science metabolism regulation moonlighting protein protein-protein interaction biomolecular condensates machine learning predictor physical interactions phase separation liquid–liquid phase separation biomineralization calcium carbonate otoliths nucleation pathways nickel intrinsically disordered regions lung cancer nmr isothermal titration calorimetry circular dichroism light scattering Dss1 intrinsically disordered protein IDPs molecular dynamics sequence composition SAXS membrane-less organelles stress long foldable segments pyHCA soluble domains protein sequence conditional order hidden order dark proteomes intrinsically disordered domains coexistence line tumor suppressor p53 intramolecular interaction salt-dependent binding affinity counterion condensation theory DNA binding fluorescence anisotropy van’t Hoff protein purification affinity chromatography Tau androgen receptor (AF1) isoform large-scale analysis protein structure AlphaFold canonical protein alpha-synuclein membrane synaptic vesicle synapsin Parkinson’s Myc drug targets SLiM small-molecule inhibitors glutamate receptor discrete molecular dynamics single molecule fluorescence integrative structural biology unfolded unstructured flexible protein function polymer physics percolation entanglement topology polymer rheology D/E repeats K/R repeats molecular dynamics simulations hub proteins multivalency transcription factor linker length heterogeneity dimers duplexes coarse-grained simulation molecular mass LLPS stability FUS n/a
Acesso em linha:	https://directory.doabooks.org/handle/20.500.12854/128609
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Physics of Protein Folding, Misfolding, and Intrinsic Disorder: A Themed Issue in Honour of Professor Vladimir Uversky on the Occasion of His 60th Birthday

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