Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations.

per Wijnen, J, Khan, P M, Vasen, H, van der Klift, H, Mulder, A, van Leeuwen-Cornelisse, I, Bakker, B, Losekoot, M, Møller, P, Fodde, R
Publicat 1997

Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16.

per Wijnen, J., Khan, P. M., Vasen, H., Menko, F., van der Klift, H., van den Broek, M., van Leeuwen-Cornelisse, I., Nagengast, F., Meijers-Heijboer, E. J., Lindhout, D., Griffioen, G., Cats, A., Kleibeuker, J., Varesco, L., Bertario, L., Bisgaard, M. L., Mohr, J., Kolodner, R., Fodde, R.
Publicat 1996