A Combined Human in Silico and CRISPR/Cas9-Mediated in Vivo Zebrafish Based Approach to Provide Phenotypic Data for Supporting Early Target Validation

Por Matthew J. Winter, Yosuke Ono, Jonathan S. Ball, Anna Walentinsson, Erik Michaelsson, Anna Tochwin, Steffen Scholpp, Charles R. Tyler, Steve Rees, Malcolm J Hetheridge, Mohammad Bohlooly-Y
Publicado em 2022-04-01

PAI-1 in granulosa cells is suppressed directly by statin and indirectly by suppressing TGF-β and TNF-α in mononuclear cells by insulin sensitizing drugs

Por Yamada-Nomoto, Kaori, Yoshino, Osamu, Akiyama, Ikumi, Iwase, Akira, Yosuke, Ono, Nakamura, Tomoko, Harada, Miyuki, Nakashima, Akitoshi, Shima, Tomoko, Ushijima, Akemi, Osuga, Yutaka, Chang, R. Jeffery, Shimasaki, Shunichi, Saito, Shigeru
Publicado no Am J Reprod Immunol (2017)

Relaxin-2 May Suppress Endometriosis by Reducing Fibrosis, Scar Formation, and Inflammation

Por Osamu Yoshino, Yosuke Ono, Masako Honda, Kyoko Hattori, Erina Sato, Takehiro Hiraoka, Masami Ito, Mutsumi Kobayashi, Kenta Arai, Hidekazu Katayama, Hiroyoshi Tsuchida, Kaori Yamada-Nomoto, Shunsuke Iwahata, Yoshiyuki Fukushi, Shinichiro Wada, Haruko Iwase, Kaori Koga, Yutaka Osuga, Michio Iwaoka, Nobuya Unno
Publicado em 2020-10-01