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Calmodulin and Ca(2+) control of voltage gated Na(+) channels

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Bilobal architecture is a requirement for calmodulin signaling to Ca(V)1.3 channels

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Ca(2+)-dependent regulation of sodium channels Na(V)1.4 and Na(V)1.5 is controlled by the post-IQ motif

od Yoder, Jesse B., Ben-Johny, Manu, Farinelli, Federica, Srinivasan, Lakshmi, Shoemaker, Sophie R., Tomaselli, Gordon F., Gabelli, Sandra B., Amzel, L. Mario
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Structural basis of cytoplasmic Na(V)1.5 and Na(V)1.4 regulation

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Regulation of the Na(v)1.5 cytoplasmic domain by Calmodulin

od Gabelli, Sandra B., Boto, Agedi, HalperinKuhns, Victoria, Bianchet, Mario A., Farinelli, Federica, Aripirala, Srinivas, Yoder, Jesse, Jakoncic, Jean, Tomaselli, Gordon F., Amzel, L. Mario
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Calcium Triggers Reversal of Calmodulin on Nested Anti-Parallel Sites in the IQ Motif of the Neuronal Voltage-Dependent Sodium Channel Na(V)1.2

od Hovey, Liam, Fowler, C. Andrew, Mahling, Ryan, Lin, Zesen, Miller, Mark Stephen, Marx, Dagan C., Yoder, Jesse B., Kim, Elaine H., Tefft, Kristin M., Waite, Brett C., Feldkamp, Michael D., Yu, Liping, Shea, Madeline A.
Wydane w Biophys Chem (2017)