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Calmodulin and Ca(2+) control of voltage gated Na(+) channels

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Bilobal architecture is a requirement for calmodulin signaling to Ca(V)1.3 channels

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Vydáno v Proc Natl Acad Sci U S A (2018)

Ca(2+)-dependent regulation of sodium channels Na(V)1.4 and Na(V)1.5 is controlled by the post-IQ motif

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Vydáno v Nat Commun (2019)

Structural basis of cytoplasmic Na(V)1.5 and Na(V)1.4 regulation

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Regulation of the Na(v)1.5 cytoplasmic domain by Calmodulin

Autor Gabelli, Sandra B., Boto, Agedi, HalperinKuhns, Victoria, Bianchet, Mario A., Farinelli, Federica, Aripirala, Srinivas, Yoder, Jesse, Jakoncic, Jean, Tomaselli, Gordon F., Amzel, L. Mario
Vydáno v Nat Commun (2014)

Calcium Triggers Reversal of Calmodulin on Nested Anti-Parallel Sites in the IQ Motif of the Neuronal Voltage-Dependent Sodium Channel Na(V)1.2

Autor Hovey, Liam, Fowler, C. Andrew, Mahling, Ryan, Lin, Zesen, Miller, Mark Stephen, Marx, Dagan C., Yoder, Jesse B., Kim, Elaine H., Tefft, Kristin M., Waite, Brett C., Feldkamp, Michael D., Yu, Liping, Shea, Madeline A.
Vydáno v Biophys Chem (2017)