Trametinib inhibits RAS-mutant MLL-rearranged acute lymphoblastic leukemia at specific niche sites and reduces ERK phosphorylation in vivo

door Kerstjens, Mark, Pinhancos, Sandra S., Castro, Patricia Garrido, Schneider, Pauline, Wander, Priscilla, Pieters, Rob, Stam, Ronald W.
Gepubliceerd in Haematologica (2018)

Irinotecan Induces Disease Remission in Xenograft Mouse Models of Pediatric MLL-Rearranged Acute Lymphoblastic Leukemia

door Kerstjens, Mark, Garrido Castro, Patricia, Pinhanços, Sandra S., Schneider, Pauline, Wander, Priscilla, Pieters, Rob, Stam, Ronald W.
Gepubliceerd in Biomedicines (2021)

FLT3(N676K) drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis

door Hyrenius-Wittsten, Axel, Pilheden, Mattias, Falqués-Costa, Antoni, Eriksson, Mia, Sturesson, Helena, Schneider, Pauline, Wander, Priscilla, Garcia-Ruiz, Cristian, Liu, Jian, Ågerstam, Helena, Hultquist, Anne, Lilljebjörn, Henrik, Stam, Ronald W., Järås, Marcus, Hagström-Andersson, Anna K.
Gepubliceerd in Leukemia (2019)

The clinical and biological characteristics of NUP98-KDM5A pediatric acute myeloid leukemia

door Noort, Sanne, Wander, Priscilla, Alonzo, Todd A., Smith, Jenny, Ries, Rhonda E., Gerbing, Robert B., Dolman, M. Emmy M., Locatelli, Franco, Reinhardt, Dirk, Baruchel, Andre, Stary, Jan, Molenaar, Jan J., Stam, Ronald W., van den Heuvel-Eibrink, Marry M., Zwaan, C. Michel, Meshinchi, Soheil
Gepubliceerd in Haematologica (2020)

High-throughput drug screening reveals Pyrvinium pamoate as effective candidate against pediatric MLL-rearranged acute myeloid leukemia

door Wander, Priscilla, Arentsen-Peters, Susan T.C.J.M., Pinhanҫos, Sandra S., Koopmans, Bianca, Dolman, M.Emmy M., Ariese, Rijndert, Bos, Frank L., Castro, Patricia Garrido, Jones, Luke, Schneider, Pauline, Navarro, Miriam Guillen, Molenaar, Jan J., Rios, Anne C., Zwaan, C. Michel, Stam, Ronald W.
Gepubliceerd in Transl Oncol (2021)