In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib

Autor Rolf, Michael G, Curwen, Jon O, Veldman-Jones, Margaret, Eberlein, Cath, Wang, Jianyan, Harmer, Alex, Hellawell, Caroline J, Braddock, Martin
Vydáno v Pharmacol Res Perspect (2015)

The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment

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Vydáno v J Immunother Cancer (2017)