Apolipoprotein E4 impairs neuronal insulin signaling by trapping insulin receptor in the endosomes

Yazar: Zhao, Na, Liu, Chia-Chen, Van Ingelgom, Alexandra J., Martens, Yuka A., Linares, Cynthia, Knight, Joshua A., Painter, Meghan M., Sullivan, Patrick M., Bu, Guojun
Yayımlandı Neuron (2017)

APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid

Yazar: Zhao, Na, Attrebi, Olivia N., Ren, Yingxue, Qiao, Wenhui, Sonustun, Berkiye, Martens, Yuka A., Meneses, Axel D., Li, Fuyao, Shue, Francis, Zheng, Jiaying, Van Ingelgom, Alexandra J., Davis, Mary D., Kurti, Aishe, Knight, Joshua A., Linares, Cynthia, Chen, Yixing, Delenclos, Marion, Liu, Chia-Chen, Fryer, John D., Asmann, Yan W., McLean, Pamela J., Dickson, Dennis W., Ross, Owen A., Bu, Guojun
Yayımlandı Sci Transl Med (2020)

APOE ε2 is associated with increased tau pathology in primary tauopathy

Yazar: Zhao, Na, Liu, Chia-Chen, Van Ingelgom, Alexandra J., Linares, Cynthia, Kurti, Aishe, Knight, Joshua A., Heckman, Michael G., Diehl, Nancy N., Shinohara, Mitsuru, Martens, Yuka A., Attrebi, Olivia N., Petrucelli, Leonard, Fryer, John D., Wszolek, Zbigniew K., Graff-Radford, Neill R., Caselli, Richard J., Sanchez-Contreras, Monica Y., Rademakers, Rosa, Murray, Melissa E., Koga, Shunsuke, Dickson, Dennis W., Ross, Owen A., Bu, Guojun
Yayımlandı Nat Commun (2018)