Apolipoprotein E4 impairs neuronal insulin signaling by trapping insulin receptor in the endosomes

di Zhao, Na, Liu, Chia-Chen, Van Ingelgom, Alexandra J., Martens, Yuka A., Linares, Cynthia, Knight, Joshua A., Painter, Meghan M., Sullivan, Patrick M., Bu, Guojun
Pubblicato in Neuron (2017)

APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid

di Zhao, Na, Attrebi, Olivia N., Ren, Yingxue, Qiao, Wenhui, Sonustun, Berkiye, Martens, Yuka A., Meneses, Axel D., Li, Fuyao, Shue, Francis, Zheng, Jiaying, Van Ingelgom, Alexandra J., Davis, Mary D., Kurti, Aishe, Knight, Joshua A., Linares, Cynthia, Chen, Yixing, Delenclos, Marion, Liu, Chia-Chen, Fryer, John D., Asmann, Yan W., McLean, Pamela J., Dickson, Dennis W., Ross, Owen A., Bu, Guojun
Pubblicato in Sci Transl Med (2020)

APOE ε2 is associated with increased tau pathology in primary tauopathy

di Zhao, Na, Liu, Chia-Chen, Van Ingelgom, Alexandra J., Linares, Cynthia, Kurti, Aishe, Knight, Joshua A., Heckman, Michael G., Diehl, Nancy N., Shinohara, Mitsuru, Martens, Yuka A., Attrebi, Olivia N., Petrucelli, Leonard, Fryer, John D., Wszolek, Zbigniew K., Graff-Radford, Neill R., Caselli, Richard J., Sanchez-Contreras, Monica Y., Rademakers, Rosa, Murray, Melissa E., Koga, Shunsuke, Dickson, Dennis W., Ross, Owen A., Bu, Guojun
Pubblicato in Nat Commun (2018)