Apolipoprotein E4 impairs neuronal insulin signaling by trapping insulin receptor in the endosomes

por Zhao, Na, Liu, Chia-Chen, Van Ingelgom, Alexandra J., Martens, Yuka A., Linares, Cynthia, Knight, Joshua A., Painter, Meghan M., Sullivan, Patrick M., Bu, Guojun
Publicado en Neuron (2017)

APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid

por Zhao, Na, Attrebi, Olivia N., Ren, Yingxue, Qiao, Wenhui, Sonustun, Berkiye, Martens, Yuka A., Meneses, Axel D., Li, Fuyao, Shue, Francis, Zheng, Jiaying, Van Ingelgom, Alexandra J., Davis, Mary D., Kurti, Aishe, Knight, Joshua A., Linares, Cynthia, Chen, Yixing, Delenclos, Marion, Liu, Chia-Chen, Fryer, John D., Asmann, Yan W., McLean, Pamela J., Dickson, Dennis W., Ross, Owen A., Bu, Guojun
Publicado en Sci Transl Med (2020)

APOE ε2 is associated with increased tau pathology in primary tauopathy

por Zhao, Na, Liu, Chia-Chen, Van Ingelgom, Alexandra J., Linares, Cynthia, Kurti, Aishe, Knight, Joshua A., Heckman, Michael G., Diehl, Nancy N., Shinohara, Mitsuru, Martens, Yuka A., Attrebi, Olivia N., Petrucelli, Leonard, Fryer, John D., Wszolek, Zbigniew K., Graff-Radford, Neill R., Caselli, Richard J., Sanchez-Contreras, Monica Y., Rademakers, Rosa, Murray, Melissa E., Koga, Shunsuke, Dickson, Dennis W., Ross, Owen A., Bu, Guojun
Publicado en Nat Commun (2018)