PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRas

por Klein, Christian H., Truxius, Dina C., Vogel, Holger A., Harizanova, Jana, Murarka, Sandip, Martín‐Gago, Pablo, Bastiaens, Philippe I.H.
Publicado en Int J Cancer (2018)

Identification of pyrazolopyridazinones as PDEδ inhibitors

por Papke, Björn, Murarka, Sandip, Vogel, Holger A, Martín-Gago, Pablo, Kovacevic, Marija, Truxius, Dina C, Fansa, Eyad K, Ismail, Shehab, Zimmermann, Gunther, Heinelt, Kaatje, Schultz-Fademrecht, Carsten, Al Saabi, Alaa, Baumann, Matthias, Nussbaumer, Peter, Wittinghofer, Alfred, Waldmann, Herbert, Bastiaens, Philippe I.H.
Publicado en Nat Commun (2016)