Aging and the cardiac collagen matrix: Novel mediators of fibrotic remodelling

door Horn, Margaux A., Trafford, Andrew W.
Gepubliceerd in J Mol Cell Cardiol (2016)

A model model: a commentary on DiFrancesco and Noble (1985) ‘A model of cardiac electrical activity incorporating ionic pumps and concentration changes’

door Dibb, Katharine, Trafford, Andrew, Zhang, Henggui, Eisner, David
Gepubliceerd in Philos Trans R Soc Lond B Biol Sci (2015)

Calcium and Excitation-Contraction Coupling in the Heart

door Eisner, David A., Caldwell, Jessica L., Kistamás, Kornél, Trafford, Andrew W.
Gepubliceerd in Circ Res (2017)

A computational model of spatio-temporal cardiac intracellular calcium handling with realistic structure and spatial flux distribution from sarcoplasmic reticulum and t-tubule reco...

door Colman, Michael A., Pinali, Christian, Trafford, Andrew W., Zhang, Henggui, Kitmitto, Ashraf
Gepubliceerd in PLoS Comput Biol (2017)

Phosphodiesterase-5 inhibitors and the heart: compound cardioprotection?

door Hutchings, David Charles, Anderson, Simon George, Caldwell, Jessica L, Trafford, Andrew W
Gepubliceerd in Heart (2018)

The Control of Diastolic Calcium in the Heart: Basic Mechanisms and Functional Implications

door Eisner, David A., Caldwell, Jessica L., Trafford, Andrew W., Hutchings, David C.
Gepubliceerd in Circ Res (2020)

Direct measurements of SR free Ca reveal the mechanism underlying the transient effects of RyR potentiation under physiological conditions

door Greensmith, David J., Galli, Gina L.J., Trafford, Andrew W., Eisner, David A.
Gepubliceerd in 2014

How does CaMKIIδ phosphorylation of the cardiac ryanodine receptor contribute to inotropy?

door Eisner, David A., George, Christopher H., Smith, Godfrey L., Trafford, Andrew W., Venetucci, Luigi A.
Gepubliceerd in 2010

Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes

door Briston, Sarah J., Dibb, Katharine M., Solaro, R. John, Eisner, David A., Trafford, Andrew W.
Gepubliceerd in Cardiovasc Res (2014)

Human junctophilin-2 undergoes a structural rearrangement upon binding PtdIns(3,4,5)P(3) and the S101R mutation identified in hypertrophic cardiomyopathy obviates this response

door Bennett, Hayley J., Davenport, John Bernard, Collins, Richard F., Trafford, Andrew W., Pinali, Christian, Kitmitto, Ashraf
Gepubliceerd in 2013

Localised micro-mechanical stiffening in the ageing aorta

door Graham, Helen K., Akhtar, Riaz, Kridiotis, Constantinos, Derby, Brian, Kundu, Tribikram, Trafford, Andrew W., Sherratt, Michael J.
Gepubliceerd in 2011

Three-Dimensional Structure of the Intercalated Disc Reveals Plicate Domain and Gap Junction Remodeling in Heart Failure

door Pinali, Christian, Bennett, Hayley J., Davenport, J. Bernard, Caldwell, Jessica L., Starborg, Tobias, Trafford, Andrew W., Kitmitto, Ashraf
Gepubliceerd in Biophys J (2015)

Increased Ca buffering underpins remodelling of Ca(2+) handling in old sheep atrial myocytes

door Clarke, Jessica D., Caldwell, Jessica L., Pearman, Charles M., Eisner, David A., Trafford, Andrew W., Dibb, Katharine M.
Gepubliceerd in J Physiol (2017)

MAPS; acute safety data of the St Jude accent - tendril IPG system during prolonged max power CMR scanning

door Ainslie, Mark P, Reid, Anna, Miller, Christopher A, Clark, David, Brown, Benjamin, Fox, David, Davidson, Neil, Trafford, Andrew, Schmitt, Matthias
Gepubliceerd in J Cardiovasc Magn Reson (2015)

Optimising Large Animal Models of Sustained Atrial Fibrillation: Relevance of the Critical Mass Hypothesis

door Denham, Nathan C., Pearman, Charles M., Madders, George W. P., Smith, Charlotte E. R., Trafford, Andrew W., Dibb, Katharine M.
Gepubliceerd in Front Physiol (2021)

Dependence of Cardiac Transverse Tubules on the BAR Domain Protein Amphiphysin II (BIN-1)

door Caldwell, Jessica L., Smith, Charlotte E.R., Taylor, Rebecca F., Kitmitto, Ashraf, Eisner, David A., Dibb, Katharine M., Trafford, Andrew W.
Gepubliceerd in Circ Res (2014)

Postnatal enalapril to Improve Cardiovascular fUnction following preterm Preeclampsia (PICk-UP): a randomised double-blind placebo-controlled feasibility trial

door Ormesher, Laura, Higson, Suzanne, Luckie, Matthew, Roberts, Stephen A, Glossop, Heather, Trafford, Andrew, Cottrell, Elizabeth, Johnstone, Edward D, Myers, Jenny E
Gepubliceerd in Hypertension (2020)

Calcium in the Pathophysiology of Atrial Fibrillation and Heart Failure

door Denham, Nathan C., Pearman, Charles M., Caldwell, Jessica L., Madders, George W. P., Eisner, David A., Trafford, Andrew W., Dibb, Katharine M.
Gepubliceerd in Front Physiol (2018)

Chronic vagal nerve stimulation has no effect on tachycardia‐induced heart failure progression or excitation–contraction coupling

door Radcliffe, Emma J., Pearman, Charles M., Watkins, Amy, Lawless, Michael, Kirkwood, Graeme J., Saxton, Sophie N., Eisner, David A., Trafford, Andrew W.
Gepubliceerd in Physiol Rep (2020)

Phosphodiesterase type-5 inhibitor use in type 2 diabetes is associated with a reduction in all-cause mortality

door Anderson, Simon G, Hutchings, David C, Woodward, Mark, Rahimi, Kazem, Rutter, Martin K, Kirby, Mike, Hackett, Geoff, Trafford, Andrew W, Heald, Adrian H
Gepubliceerd in Heart (2016)