Scalable syntheses of the BET bromodomain inhibitor JQ1

por Syeda, Shameem Sultana, Jakkaraj, Sudhakar, Georg, Gunda I.
Publicado en Tetrahedron Lett (2015)

Design, Synthesis, and in Vitro and in Vivo Evaluation of Ouabain Analogues as Potent and Selective Na,K-ATPase α4 Isoform Inhibitors for Male Contraception

por Syeda, Shameem Sultana, Sánchez, Gladis, Hong, Kwon Ho, Hawkinson, Jon E., Georg, Gunda I., Blanco, Gustavo
Publicado en J Med Chem (2018)

The Na(+) and K(+) transport system of sperm (ATP1A4) is essential for male fertility and an attractive target for male contraception

por Syeda, Shameem Sultana, Sánchez, Gladis, McDermott, Jeffrey P, Hong, Kwon Ho, Blanco, Gustavo, Georg, Gunda I
Publicado en Biol Reprod (2020)

The Fungal Sexual Pheromone Sirenin Activates the Human CatSper Channel Complex

por Syeda, Shameem Sultana, Carlson, Erick J., Miller, Melissa R., Francis, Rawle, Clapham, David E., Lishko, Polina V., Hawkinson, Jon E., Hook, Derek, Georg, Gunda I.
Publicado en ACS Chem Biol (2015)