Autoimmune disease-associated gene expression is reduced by BET-inhibition

Por Janneke G.C. Peeters, Stephin J. Vervoort, Gerdien Mijnheer, Sytze de Roock, Sebastiaan J. Vastert, Edward E.S. Nieuwenhuis, Femke van Wijk, Berent J. Prakken, Michal Mokry, Jorg van Loosdregt
Publicado em 2016-03-01

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

Por Simon J. Hogg, Stephin J. Vervoort, Sumit Deswal, Christopher J. Ott, Jason Li, Leonie A. Cluse, Paul A. Beavis, Phillip K. Darcy, Benjamin P. Martin, Andrew Spencer, Anna K. Traunbauer, Irina Sadovnik, Karin Bauer, Peter Valent, James E. Bradner, Johannes Zuber, Jake Shortt, Ricky W. Johnstone
Publicado em 2017-02-01