Using Peptidomimetics and Constrained Peptides as Valuable Tools for Inhibiting Protein–Protein Interactions

由 Robertson, Naomi S., Spring, David R.
發表在 Molecules (2018)

Rational Methods for the Selection of Diverse Screening Compounds

由 Huggins, David J., Venkitaraman, Ashok R., Spring, David R.
發表在 ACS Chem Biol (2011)

Divergent Synthesis of Quinolone Natural Products from Pseudonocardia sp. CL38489

由 Geddis, Stephen M., Carro, Laura, Hodgkinson, James T., Spring, David R.
發表在 European J Org Chem (2016)

Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics

由 Charoenpattarapreeda, Jiraborrirak, Walsh, Stephen J., Carroll, Jason S., Spring, David R.
發表在 Angew Chem Int Ed Engl (2020)

A new Pseudomonas quinolone signal (PQS) binding partner: MexG

由 Hodgkinson, James T., Gross, Jeremy, Baker, Ysobel R., Spring, David R., Welch, M.
發表在 Chem Sci (2016)

Synthesis and Reactivity of a Bis-Strained Alkyne Derived from 1,1′-Biphenyl-2,2′,6,6′-tetrol

由 Knighton, Richard C., Sharma, Krishna, Robertson, Naomi S., Spring, David R., Wills, Martin
發表在 ACS Omega (2019)

A quorum-sensing molecule acts as a morphogen controlling gas vesicle organelle biogenesis and adaptive flotation in an enterobacterium

由 Ramsay, Joshua P., Williamson, Neil R., Spring, David R., Salmond, George P. C.
出版 2011

Quantitatively Mapping Cellular Viscosity with Detailed Organelle Information via a Designed PET Fluorescent Probe

由 Liu, Tianyu, Liu, Xiaogang, Spring, David R., Qian, Xuhong, Cui, Jingnan, Xu, Zhaochao
出版 2014

Structural and calorimetric studies demonstrate that the hepatocyte nuclear factor 1β (HNF1β) transcription factor is imported into the nucleus via a monopartite NLS sequence

由 Wiedmann, Mareike M., Aibara, Shintaro, Spring, David R., Stewart, Murray, Brenton, James D.
發表在 J Struct Biol (2016)

Design and Synthesis of a Biotinylated Chemical Probe for Detecting the Molecular Targets of an Inhibitor of the Production of the Pseudomonas aeruginosa Virulence Factor Pyocyanin

由 Baker, Ysobel R., Galloway, Warren R. J. D., Hodgkinson, James T., Spring, David R.
發表在 Molecules (2013)

Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions

由 Laraia, Luca, McKenzie, Grahame, Spring, David R., Venkitaraman, Ashok R., Huggins, David J.
發表在 Chem Biol (2015)

Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections

由 Kidd, Sarah L., Osberger, Thomas J., Mateu, Natalia, Sore, Hannah F., Spring, David R.
發表在 Front Chem (2018)

Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products

由 Geddis, Stephen M, Coroama, Teodora, Forrest, Suzanne, Hodgkinson, James T, Welch, Martin, Spring, David R
發表在 Beilstein J Org Chem (2018)

Structure-Activity Analysis of the Pseudomonas Quinolone Signal Molecule

由 Hodgkinson, James, Bowden, Steven D., Galloway, Warren R. J. D., Spring, David R., Welch, Martin
出版 2010

Stereocontrolled semi-syntheses of deguelin and tephrosin

由 Russell, David A., Freudenreich, Julien J., Ciardiello, Joe J., Sore, Hannah F., Spring, David R.
發表在 Org Biomol Chem (2017)

Diversity-oriented synthesis of heterocycles and macrocycles by controlled reactions of oxetanes with α-iminocarbenes

由 Guarnieri-Ibáñez, Alejandro, Medina, Florian, Besnard, Céline, Kidd, Sarah L., Spring, David R., Lacour, Jérôme
發表在 Chem Sci (2017)

Rapid and robust cysteine bioconjugation with vinylheteroarenes

由 Seki, Hikaru, Walsh, Stephen J., Bargh, Jonathan D., Parker, Jeremy S., Carroll, Jason, Spring, David R.
發表在 Chem Sci (2021)

Two-directional synthesis as a tool for diversity-oriented synthesis: Synthesis of alkaloid scaffolds

由 O’Connell, Kieron M G, Díaz-Gavilán, Monica, Galloway, Warren R J D, Spring, David R
出版 2012

High Content Screening of Diverse Compound Libraries Identifies Potent Modulators of Tubulin Dynamics

由 Laraia, Luca, Stokes, Jamie, Emery, Amy, McKenzie, Grahame J., Venkitaraman, Ashok R., Spring, David R.
出版 2014

Downfalls of Chemical Probes Acting at the Kinase ATP-Site: CK2 as a Case Study

由 Atkinson, Eleanor L., Iegre, Jessica, Brear, Paul D., Zhabina, Elizabeth A., Hyvönen, Marko, Spring, David R.
發表在 Molecules (2021)