Using Peptidomimetics and Constrained Peptides as Valuable Tools for Inhibiting Protein–Protein Interactions

von Robertson, Naomi S., Spring, David R.
Veröffentlicht in Molecules (2018)

Rational Methods for the Selection of Diverse Screening Compounds

von Huggins, David J., Venkitaraman, Ashok R., Spring, David R.
Veröffentlicht in ACS Chem Biol (2011)

Divergent Synthesis of Quinolone Natural Products from Pseudonocardia sp. CL38489

von Geddis, Stephen M., Carro, Laura, Hodgkinson, James T., Spring, David R.
Veröffentlicht in European J Org Chem (2016)

Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics

von Charoenpattarapreeda, Jiraborrirak, Walsh, Stephen J., Carroll, Jason S., Spring, David R.
Veröffentlicht in Angew Chem Int Ed Engl (2020)

A new Pseudomonas quinolone signal (PQS) binding partner: MexG

von Hodgkinson, James T., Gross, Jeremy, Baker, Ysobel R., Spring, David R., Welch, M.
Veröffentlicht in Chem Sci (2016)

Synthesis and Reactivity of a Bis-Strained Alkyne Derived from 1,1′-Biphenyl-2,2′,6,6′-tetrol

von Knighton, Richard C., Sharma, Krishna, Robertson, Naomi S., Spring, David R., Wills, Martin
Veröffentlicht in ACS Omega (2019)

A quorum-sensing molecule acts as a morphogen controlling gas vesicle organelle biogenesis and adaptive flotation in an enterobacterium

von Ramsay, Joshua P., Williamson, Neil R., Spring, David R., Salmond, George P. C.
Veröffentlicht 2011

Quantitatively Mapping Cellular Viscosity with Detailed Organelle Information via a Designed PET Fluorescent Probe

von Liu, Tianyu, Liu, Xiaogang, Spring, David R., Qian, Xuhong, Cui, Jingnan, Xu, Zhaochao
Veröffentlicht 2014

Structural and calorimetric studies demonstrate that the hepatocyte nuclear factor 1β (HNF1β) transcription factor is imported into the nucleus via a monopartite NLS sequence

von Wiedmann, Mareike M., Aibara, Shintaro, Spring, David R., Stewart, Murray, Brenton, James D.
Veröffentlicht in J Struct Biol (2016)

Design and Synthesis of a Biotinylated Chemical Probe for Detecting the Molecular Targets of an Inhibitor of the Production of the Pseudomonas aeruginosa Virulence Factor Pyocyanin

von Baker, Ysobel R., Galloway, Warren R. J. D., Hodgkinson, James T., Spring, David R.
Veröffentlicht in Molecules (2013)

Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions

von Laraia, Luca, McKenzie, Grahame, Spring, David R., Venkitaraman, Ashok R., Huggins, David J.
Veröffentlicht in Chem Biol (2015)

Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections

von Kidd, Sarah L., Osberger, Thomas J., Mateu, Natalia, Sore, Hannah F., Spring, David R.
Veröffentlicht in Front Chem (2018)

Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products

von Geddis, Stephen M, Coroama, Teodora, Forrest, Suzanne, Hodgkinson, James T, Welch, Martin, Spring, David R
Veröffentlicht in Beilstein J Org Chem (2018)

Structure-Activity Analysis of the Pseudomonas Quinolone Signal Molecule

von Hodgkinson, James, Bowden, Steven D., Galloway, Warren R. J. D., Spring, David R., Welch, Martin
Veröffentlicht 2010

Stereocontrolled semi-syntheses of deguelin and tephrosin

von Russell, David A., Freudenreich, Julien J., Ciardiello, Joe J., Sore, Hannah F., Spring, David R.
Veröffentlicht in Org Biomol Chem (2017)

Diversity-oriented synthesis of heterocycles and macrocycles by controlled reactions of oxetanes with α-iminocarbenes

von Guarnieri-Ibáñez, Alejandro, Medina, Florian, Besnard, Céline, Kidd, Sarah L., Spring, David R., Lacour, Jérôme
Veröffentlicht in Chem Sci (2017)

Rapid and robust cysteine bioconjugation with vinylheteroarenes

von Seki, Hikaru, Walsh, Stephen J., Bargh, Jonathan D., Parker, Jeremy S., Carroll, Jason, Spring, David R.
Veröffentlicht in Chem Sci (2021)

Two-directional synthesis as a tool for diversity-oriented synthesis: Synthesis of alkaloid scaffolds

von O’Connell, Kieron M G, Díaz-Gavilán, Monica, Galloway, Warren R J D, Spring, David R
Veröffentlicht 2012

High Content Screening of Diverse Compound Libraries Identifies Potent Modulators of Tubulin Dynamics

von Laraia, Luca, Stokes, Jamie, Emery, Amy, McKenzie, Grahame J., Venkitaraman, Ashok R., Spring, David R.
Veröffentlicht 2014

Downfalls of Chemical Probes Acting at the Kinase ATP-Site: CK2 as a Case Study

von Atkinson, Eleanor L., Iegre, Jessica, Brear, Paul D., Zhabina, Elizabeth A., Hyvönen, Marko, Spring, David R.
Veröffentlicht in Molecules (2021)