Using Peptidomimetics and Constrained Peptides as Valuable Tools for Inhibiting Protein–Protein Interactions

بواسطة Robertson, Naomi S., Spring, David R.
الحاوية / القاعدة Molecules (2018)

Rational Methods for the Selection of Diverse Screening Compounds

بواسطة Huggins, David J., Venkitaraman, Ashok R., Spring, David R.
الحاوية / القاعدة ACS Chem Biol (2011)

Divergent Synthesis of Quinolone Natural Products from Pseudonocardia sp. CL38489

بواسطة Geddis, Stephen M., Carro, Laura, Hodgkinson, James T., Spring, David R.
الحاوية / القاعدة European J Org Chem (2016)

Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics

بواسطة Charoenpattarapreeda, Jiraborrirak, Walsh, Stephen J., Carroll, Jason S., Spring, David R.
الحاوية / القاعدة Angew Chem Int Ed Engl (2020)

A new Pseudomonas quinolone signal (PQS) binding partner: MexG

بواسطة Hodgkinson, James T., Gross, Jeremy, Baker, Ysobel R., Spring, David R., Welch, M.
الحاوية / القاعدة Chem Sci (2016)

Synthesis and Reactivity of a Bis-Strained Alkyne Derived from 1,1′-Biphenyl-2,2′,6,6′-tetrol

بواسطة Knighton, Richard C., Sharma, Krishna, Robertson, Naomi S., Spring, David R., Wills, Martin
الحاوية / القاعدة ACS Omega (2019)

A quorum-sensing molecule acts as a morphogen controlling gas vesicle organelle biogenesis and adaptive flotation in an enterobacterium

بواسطة Ramsay, Joshua P., Williamson, Neil R., Spring, David R., Salmond, George P. C.
منشور في 2011

Quantitatively Mapping Cellular Viscosity with Detailed Organelle Information via a Designed PET Fluorescent Probe

بواسطة Liu, Tianyu, Liu, Xiaogang, Spring, David R., Qian, Xuhong, Cui, Jingnan, Xu, Zhaochao
منشور في 2014

Structural and calorimetric studies demonstrate that the hepatocyte nuclear factor 1β (HNF1β) transcription factor is imported into the nucleus via a monopartite NLS sequence

بواسطة Wiedmann, Mareike M., Aibara, Shintaro, Spring, David R., Stewart, Murray, Brenton, James D.
الحاوية / القاعدة J Struct Biol (2016)

Design and Synthesis of a Biotinylated Chemical Probe for Detecting the Molecular Targets of an Inhibitor of the Production of the Pseudomonas aeruginosa Virulence Factor Pyocyanin

بواسطة Baker, Ysobel R., Galloway, Warren R. J. D., Hodgkinson, James T., Spring, David R.
الحاوية / القاعدة Molecules (2013)

Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions

بواسطة Laraia, Luca, McKenzie, Grahame, Spring, David R., Venkitaraman, Ashok R., Huggins, David J.
الحاوية / القاعدة Chem Biol (2015)

Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections

بواسطة Kidd, Sarah L., Osberger, Thomas J., Mateu, Natalia, Sore, Hannah F., Spring, David R.
الحاوية / القاعدة Front Chem (2018)

Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products

بواسطة Geddis, Stephen M, Coroama, Teodora, Forrest, Suzanne, Hodgkinson, James T, Welch, Martin, Spring, David R
الحاوية / القاعدة Beilstein J Org Chem (2018)

Structure-Activity Analysis of the Pseudomonas Quinolone Signal Molecule

بواسطة Hodgkinson, James, Bowden, Steven D., Galloway, Warren R. J. D., Spring, David R., Welch, Martin
منشور في 2010

Stereocontrolled semi-syntheses of deguelin and tephrosin

بواسطة Russell, David A., Freudenreich, Julien J., Ciardiello, Joe J., Sore, Hannah F., Spring, David R.
الحاوية / القاعدة Org Biomol Chem (2017)

Diversity-oriented synthesis of heterocycles and macrocycles by controlled reactions of oxetanes with α-iminocarbenes

بواسطة Guarnieri-Ibáñez, Alejandro, Medina, Florian, Besnard, Céline, Kidd, Sarah L., Spring, David R., Lacour, Jérôme
الحاوية / القاعدة Chem Sci (2017)

Rapid and robust cysteine bioconjugation with vinylheteroarenes

بواسطة Seki, Hikaru, Walsh, Stephen J., Bargh, Jonathan D., Parker, Jeremy S., Carroll, Jason, Spring, David R.
الحاوية / القاعدة Chem Sci (2021)

Two-directional synthesis as a tool for diversity-oriented synthesis: Synthesis of alkaloid scaffolds

بواسطة O’Connell, Kieron M G, Díaz-Gavilán, Monica, Galloway, Warren R J D, Spring, David R
منشور في 2012

High Content Screening of Diverse Compound Libraries Identifies Potent Modulators of Tubulin Dynamics

بواسطة Laraia, Luca, Stokes, Jamie, Emery, Amy, McKenzie, Grahame J., Venkitaraman, Ashok R., Spring, David R.
منشور في 2014

Downfalls of Chemical Probes Acting at the Kinase ATP-Site: CK2 as a Case Study

بواسطة Atkinson, Eleanor L., Iegre, Jessica, Brear, Paul D., Zhabina, Elizabeth A., Hyvönen, Marko, Spring, David R.
الحاوية / القاعدة Molecules (2021)