A Randomized Study of the Relative Pharmacokinetics, Pharmacodynamics, and Safety of Alirocumab, a Fully Human Monoclonal Antibody to PCSK9, After Single Subcutaneous Administratio...

بواسطة Lunven, Catherine, Paehler, Tobias, Poitiers, Franck, Brunet, Aurélie, Rey, Jacques, Hanotin, Corinne, Sasiela, William J
الحاوية / القاعدة Cardiovasc Ther (2014)

Simulation of Lipid-Lowering Therapy Intensification in a Population With Atherosclerotic Cardiovascular Disease

بواسطة Cannon, Christopher P., Khan, Irfan, Klimchak, Alexa C., Reynolds, Matthew R., Sanchez, Robert J., Sasiela, William J.
الحاوية / القاعدة JAMA Cardiol (2017)

Relationship Between Low‐Density Lipoprotein Cholesterol, Free Proprotein Convertase Subtilisin/Kexin Type 9, and Alirocumab Levels After Different Lipid‐Lowering Strategies

بواسطة Rey, Jacques, Poitiers, Franck, Paehler, Tobias, Brunet, Aurélie, DiCioccio, A. Thomas, Cannon, Christopher P., Surks, Howard K., Pinquier, Jean‐Louis, Hanotin, Corinne, Sasiela, William J.
الحاوية / القاعدة J Am Heart Assoc (2016)

Inhibition of Angiopoietin-Like Protein 3 With a Monoclonal Antibody Reduces Triglycerides in Hypertriglyceridemia

بواسطة Ahmad, Zahid, Banerjee, Poulabi, Hamon, Sara, Chan, Kuo-Chen, Bouzelmat, Aurelie, Sasiela, William J., Pordy, Robert, Mellis, Scott, Dansky, Hayes, Gipe, Daniel A., Dunbar, Richard L.
الحاوية / القاعدة Circulation (2019)

Alirocumab inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin

بواسطة Kühnast, Susan, van der Hoorn, José W. A., Pieterman, Elsbet J., van den Hoek, Anita M., Sasiela, William J., Gusarova, Viktoria, Peyman, Anusch, Schäfer, Hans-Ludwig, Schwahn, Uwe, Jukema, J. Wouter, Princen, Hans M. G.
منشور في 2014

A Quantitative Systems Pharmacology Platform to Investigate the Impact of Alirocumab and Cholesterol-Lowering Therapies on Lipid Profiles and Plaque Characteristics

بواسطة Ming, Jeffrey E, Abrams, Ruth E, Bartlett, Derek W, Tao, Mengdi, Nguyen, Tu, Surks, Howard, Kudrycki, Katherine, Kadambi, Ananth, Friedrich, Christina M, Djebli, Nassim, Goebel, Britta, Koszycki, Alex, Varshnaya, Meera, Elassal, Joseph, Banerjee, Poulabi, Sasiela, William J, Reed, Michael J, Barrett, Jeffrey S, Azer, Karim
الحاوية / القاعدة Gene Regul Syst Bio (2017)

Effects of PCSK9 Inhibition With Alirocumab on Lipoprotein Metabolism in Healthy Humans

بواسطة Reyes-Soffer, Gissette, Pavlyha, Marianna, Ngai, Colleen, Thomas, Tiffany, Holleran, Stephen, Ramakrishnan, Rajasekhar, Karmally, Wahida, Nandakumar, Renu, Fontanez, Nelson, Obunike, Joseph, Marcovina, Santica M., Lichtenstein, Alice H., Matthan, Nirupa R., Matta, James, Maroccia, Magali, Becue, Frederic, Poitiers, Franck, Swanson, Brian, Cowan, Lisa, Sasiela, William J., Surks, Howard K., Ginsberg, Henry N.
الحاوية / القاعدة Circulation (2017)