Physiologically‐Based Pharmacokinetic Modeling of the Drug–Drug Interaction of the UGT Substrate Ertugliflozin Following Co‐Administration with the UGT Inhibitor Mefenamic Acid...

per Callegari, Ernesto, Lin, Jian, Tse, Susanna, Goosen, Theunis C., Sahasrabudhe, Vaishali
Publicat a CPT Pharmacometrics Syst Pharmacol (2020)

Population pharmacokinetics and exposure–response analyses of varenicline in adolescent smokers

per Fediuk, Daryl J., Sweeney, Kevin, Sahasrabudhe, Vaishali, McRae, Thomas, Byon, Wonkyung
Publicat a CPT Pharmacometrics Syst Pharmacol (2021)

Bioequivalence of Metformin in Ertugliflozin/Metformin Fixed‐Dose Combination Tablets to Canadian‐Sourced Metformin Coadministered With Ertugliflozin Under Fasted and Fed States...

per Dawra, Vikas Kumar, Pelletier, Kathleen, Matschke, Kyle, Shi, Haihong, Hickman, Anne, Zhou, Susan, Krishna, Rajesh, Sahasrabudhe, Vaishali
Publicat a Clin Pharmacol Drug Dev (2020)

Pharmacokinetic Properties of Single and Multiple Doses of Ertugliflozin, a Selective Inhibitor of SGLT2, in Healthy Chinese Subjects

per Li, Yinhua, Mu, Yuting, Shi, Haihong, Liang, Yali, Liu, Zeyuan, Matschke, Kyle, Hickman, Anne, Krishna, Rajesh, Sahasrabudhe, Vaishali
Publicat a Clin Pharmacol Drug Dev (2019)

A PK/PD study comparing twice-daily to once-daily dosing regimens of ertugliflozin in healthy subjects

per Dawra, Vikas Kumar, Liang, Yali, Shi, Haihong, Bass, Almasa, Hickman, Anne, Terra, Steven G., Zhou, Susan, Cutler, David, Sahasrabudhe, Vaishali
Publicat a Int J Clin Pharmacol Ther (2019)

End‐to‐end application of model‐informed drug development for ertugliflozin, a novel sodium‐glucose cotransporter 2 inhibitor

per Fediuk, Daryl J., Nucci, Gianluca, Dawra, Vikas K., Callegari, Ernesto, Zhou, Susan, Musante, Cynthia J., Liang, Yali, Sweeney, Kevin, Sahasrabudhe, Vaishali
Publicat a CPT Pharmacometrics Syst Pharmacol (2021)

Bioequivalence of Ertugliflozin/Metformin Fixed‐Dose Combination Tablets and Coadministration of Respective Strengths of Individual Components

per Dawra, Vikas Kumar, Liang, Yali, Wei, Hua, Pelletier, Kathleen, Shi, Haihong, Hickman, Anne, Bass, Almasa, Terra, Steven G., Zhou, Susan, Krishna, Rajesh, Sahasrabudhe, Vaishali
Publicat a Clin Pharmacol Drug Dev (2019)

Overview of the Clinical Pharmacology of Ertugliflozin, a Novel Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor

per Fediuk, Daryl J., Nucci, Gianluca, Dawra, Vikas Kumar, Cutler, David L., Amin, Neeta B., Terra, Steven G., Boyd, Rebecca A., Krishna, Rajesh, Sahasrabudhe, Vaishali
Publicat a Clin Pharmacokinet (2020)

Assessment of the Drug Interaction Potential of Ertugliflozin With Sitagliptin, Metformin, Glimepiride, or Simvastatin in Healthy Subjects

per Dawra, Vikas Kumar, Cutler, David L., Zhou, Susan, Krishna, Rajesh, Shi, Haihong, Liang, Yali, Alvey, Christine, Hickman, Anne, Saur, Didier, Terra, Steven G., Sahasrabudhe, Vaishali
Publicat a Clin Pharmacol Drug Dev (2018)

Effect of Food on the Pharmacokinetics of Ertugliflozin and Its Fixed‐Dose Combinations Ertugliflozin/Sitagliptin and Ertugliflozin/Metformin

per Sahasrabudhe, Vaishali, Fediuk, Daryl J., Matschke, Kyle, Shi, Haihong, Liang, Yali, Hickman, Anne, Bass, Almasa, Terra, Steven G., Zhou, Susan, Krishna, Rajesh, Dawra, Vikas K.
Publicat a Clin Pharmacol Drug Dev (2018)

The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism

per Eudy, Rena J, Sahasrabudhe, Vaishali, Sweeney, Kevin, Tugnait, Meera, King-Ahmad, Amanda, Near, Kristen, Loria, Paula, Banker, Mary Ellen, Piotrowski, David W, Boustany-Kari, Carine M
Publicat 2011

Bioequivalence of Ertugliflozin/Sitagliptin Fixed‐Dose Combination Tablets and Coadministration of Respective Strengths of Individual Components

per Fediuk, Daryl J., Matschke, Kyle, Liang, Yali, Pelletier, Kathleen B., Wei, Hua, Shi, Haihong, Bass, Almasa, Hickman, Anne, Terra, Steven G., Zhou, Susan, Krishna, Rajesh, Sahasrabudhe, Vaishali
Publicat a Clin Pharmacol Drug Dev (2019)

Novel Application of the Two‐Period Microtracer Approach to Determine Absolute Oral Bioavailability and Fraction Absorbed of Ertugliflozin

per Raje, Sangeeta, Callegari, Ernesto, Sahasrabudhe, Vaishali, Vaz, Alfin, Shi, Haihong, Fluhler, Eric, Woolf, Eric J., Schildknegt, Klaas, Matschke, Kyle, Alvey, Christine, Zhou, Susan, Papadopoulos, Dimitris, Fountaine, Robert, Saur, Didier, Terra, Steven G., Stevens, Lloyd, Gaunt, Daniel, Cutler, David L.
Publicat a Clin Transl Sci (2018)