Discovery of APD371: Identification of a Highly Potent and Selective CB(2) Agonist for the Treatment of Chronic Pain

door Han, Sangdon, Thoresen, Lars, Jung, Jae-Kyu, Zhu, Xiuwen, Thatte, Jayant, Solomon, Michelle, Gaidarov, Ibragim, Unett, David J., Yoon, Woo Hyun, Barden, Jeremy, Sadeque, Abu, Usmani, Amin, Chen, Chuan, Semple, Graeme, Grottick, Andrew J., Al-Shamma, Hussein, Christopher, Ronald, Jones, Robert M.
Gepubliceerd in ACS Med Chem Lett (2017)

(7-Benzyloxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acids as S1P(1) Functional Antagonists

door Buzard, Daniel J., Lopez, Luis, Moody, Jeanne, Kawasaki, Andrew, Schrader, Thomas O., Kasem, Michelle, Johnson, Ben, Zhu, Xiuwen, Thoresen, Lars, Kim, Sun Hee, Gharbaoui, Tawfik, Sengupta, Dipanjan, Calvano, Lorene, Krishnan, Ashwin, Gao, Yinghong, Semple, Graeme, Edwards, Jeff, Barden, Jeremy, Morgan, Michael, Usmani, Khawja, Chen, Chuan, Sadeque, Abu, Chen, Weichao, Christopher, Ronald J., Thatte, Jayant, Fu, Lixia, Solomon, Michelle, Whelan, Kevin, Al-Shamma, Hussien, Gatlin, Joel, Gaidarov, Ibragim, Anthony, Todd, Le, Minh, Unett, David J., Stirn, Scott, Blackburn, Anthony, Behan, Dominic P., Jones, Robert M.
Gepubliceerd in ACS Med Chem Lett (2014)

Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor

door Buzard, Daniel J., Kim, Sun Hee, Lopez, Luis, Kawasaki, Andrew, Zhu, Xiuwen, Moody, Jeanne, Thoresen, Lars, Calderon, Imelda, Ullman, Brett, Han, Sangdon, Lehmann, Juerg, Gharbaoui, Tawfik, Sengupta, Dipanjan, Calvano, Lorene, Montalban, Antonio Garrido, Ma, You-An, Sage, Carleton, Gao, Yinghong, Semple, Graeme, Edwards, Jeff, Barden, Jeremy, Morgan, Michael, Chen, Weichao, Usmani, Khawja, Chen, Chuan, Sadeque, Abu, Christopher, Ronald J., Thatte, Jayant, Fu, Lixia, Solomon, Michelle, Mills, David, Whelan, Kevin, Al-Shamma, Hussien, Gatlin, Joel, Le, Minh, Gaidarov, Ibragim, Anthony, Todd, Unett, David J., Blackburn, Anthony, Rueter, Jaimie, Stirn, Scott, Behan, Dominic P., Jones, Robert M.
Gepubliceerd in ACS Med Chem Lett (2014)