Q1-390 QH426-470 RNA modification RNA processing RNA regulatory enzyme RNA-binding protein base modification gene diversity human diseases molecular biology molecular evolution new biological functions pre-tRNA processing quality control tRNA thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics thema EDItEUR::P Mathematics and Science::PD Science: general issues thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) transcription transfer RNA translation